I've proposed the idea of playing as Zelda during the seven years Link was put away into the sacred realm in Ocarina of Time a few times before. I think for one, Nintendo should readdress Ocarina of Time at least once seeing as they're pretty content to reference it or use it somehow in each game that's followed it and secondly, they could expand on Zelda and for once really show her as the strong character she would have had to be in order to become what she did. (and no, it's not because we need more strong women, I hate that argument. we need more strong CHARACTERS, gender doesn't matter. now THERE is true equality. stop putting such emphasis on strong female characters who obtain this "strength" with nothing to back it up. this one hates that.) This way the game would be all new content and not just a remake of OoT. (which I'd love to see regardless, but NOT with the TP engine/aesthetic like FAR too many people want to see)
The game could combine elements of traditional Zelda titles like dungeoning and puzzle solving and also add elements of stealth and martial arts on Zelda's road to becoming a Sheikah. That and maybe shed some freaking light on the nearly 10 year old debate of Zelda's "transformation" into Sheik. I'd LOVE to see that settled. It's a wonder Nintendo hasn't noticed this by now, they took time to point out the infamous timeline issue which they conveniently leave out of the GAMES.

In hindsight I guess Zelda really IS a main character, but the entire Zelda franchise has centered around playing as Link so it's somewhat the same thing to give Zelda a game and Sheik is a pretty unexplored character as well as the Sheikah.